Study reveals novel insights into the molecular pathology of esophageal squamous cell carcinoma
Esophageal squamous cell carcinoma (ESCC) is a highly aggressive malignancy with poor prognosis, and understanding the ...
labiotech6d
mRNA, RNAi, circRNA, ASOs: A comparative guide to RNA therapeutics
In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.
Structural insights reveal drug target in trypanosome parasites
A new study from the Kowalinski group at EMBL Grenoble characterized the structure of an important trypanosomal protein ...
Business Insider9d
Dyne Therapeutics Receives FDA Fast Track Designation for DYNE-101 for the Treatment of Myotonic Dystrophy Type 1
It is designed to enable targeted muscle tissue delivery with the goal of reducing toxic DMPK RNA in the nucleus, releasing splicing proteins, allowing normal mRNA processing and translation of normal ...
Frontiers27d
Molecular assessment of splicing variants in a cohort of inborn errors of immunity patients: methodological approach and interpretation remarks
The final, formatted version of the article will be published soon. Background. Splicing is the molecular mechanism to produce mature messenger RNA (mRNA) before its translation into protein. It is ...
Time27d
Scientists Are Racing to Develop a New Bird Flu Vaccine
What about an mRNA vaccine for H5N1? There isn't one yet, but several companies—including Moderna, Pfizer and GlaxoSmithKline (in collaboration with CureVac)—are working on such a shot.
Yahoo Finance28d
Why Moderna Inc. (MRNA) Is Skyrocketing
In this article, we are going to take a look at where Moderna Inc. (NASDAQ:MRNA) stands against other firms end 2024 stronger with impressive gains. A lackluster trading persisted throughout the ...
The Lancet28d
Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study
aMaimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain. bUniversidad de Córdoba, Córdoba, Spain. cReina Sofia University Hospital, Córdoba, Spain. dCIBER Fisiopatología de ...