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Summary: New research reveals how a tiny chemical mark on RNA helps wire the brain during development. Scientists discovered that m6A methylation regulates the production of proteins essential for ...
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Novel class of zwitterionic phospholipids enhances mRNA deliveryDOPE-Cx can form a special structure called a "cubic phase," which helps overcome a major challenge in mRNA delivery by LNPs: endosomal escape. LNPs are taken into the cell in the form of endosomes, ...
Based on several lines of interesting data, the authors conclude that FMRP, though associated with stalled ribosomes, does not determine the position on the mRNAs at which ribosomes stall. Although ...
In this valuable study, Kumar et al., provide evidence suggesting that the p130Cas drives the formation of condensates that sprout from focal adhesions to cytoplasm and suppress translation. Pending ...
Secretary Robert F. Kennedy Jr. sparred with Democrats throughout a House budget hearing Thursday, with members accusing ...
Cancer cells can acquire energy-generating structures called mitochondria from nearby nerve cells, which seems to aid their ...
The agreement also endorses the “One Health” approach, which integrates human, animal, and environmental health.
A new gene therapy delivery device could let hospital pharmacies make personalized nanomedicines to order. This democratized ...
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While US exceptionalism may have lost some of its shine, it is worth remembering that the US stock market remains home to ...
Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...
A new gene therapy delivery device could let hospital pharmacies make personalized nanomedicines to order. This democratized ...
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