Gut

International consensus on intestinal epithelial barrier assessment and therapeutic effects in inflammatory bowel diseases clinical trials

Background and aims Restoration of intestinal barrier integrity and function in inflammatory bowel disease (IBD) has been ...
gut.bmj

Can hepatic coma be caused by a reduction of brain noradrenaline or dopamine?

Intraventricular infusions of octopamine which raised brain octopamine concentrations more than 20 000-fold resulted in reductions in brain noradrenaline and dopamine by as much as 90% without ...
gut.bmj

The autonomic nervous system in functional bowel disorders

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...
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Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer

Objective Cancer immunology is a growing field of research whose aim is to develop innovative therapies and diagnostic tests. Starting from the hypothesis that immune cells promptly respond to harmful ...
gut.bmj

Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study

Background and aims: Melatonin, a sleep promoting agent, is involved in the regulation of gastrointestinal motility and sensation. We aimed to determine if melatonin was effective in improving bowel ...
gut.bmj

Development, validation, and evaluation of the PBC-40, a disease specific health related quality of life measure for primary biliary cirrhosis

Background and aims: Study of health related quality of life (HRQOL) and the factors responsible for its impairment in primary biliary cirrhosis (PBC) has, to date, been limited. There is increasing ...
gut.bmj

The Paneth cell in disease

A systematic study of the distribution of Paneth cells in disease of the small and large intestine is described. In disease of the small intestine and appendix there is usually a fall in the number of ...
gut.bmj

Influence of dietary factors on the clinical course of ulcerative colitis: a prospective cohort study

1 Northumbria Division of the University of Newcastle upon Tyne Faculty of Medicine, Newcastle upon Tyne, UK 2 Human Nutrition Research Centre, School of Agriculture, Food and Rural Development, ...
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Hepatitis and liver dysfunction with rifampicin therapy for pruritus in primary biliary cirrhosis

Correspondence to: Dr M Prince, Centre for Liver Research, 4th Floor William Leech Building, Newcastle University Medical School, Framlington Place, Newcastle NE2 4HH, UK; Martin.prince{at}ncl.ac.uk ...
gut.bmj

CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models

Clinic for Internal Medicine I, University Hospital of Ulm, Ulm, Germany Background: CD147 (basigin, EMMPRIN) is a multifunctional, highly conserved glycoprotein enriched in pancreatic ductal ...
gut.bmj

Adherence to a Mediterranean diet is associated with a lower risk of later-onset Crohn’s disease: results from two large prospective cohort studies

Objective To examine the relationship between Mediterranean diet and risk of later-onset Crohn’s disease (CD) or ulcerative colitis (UC). Design We conducted a prospective cohort study of 83 147 ...