Asthma, an inflammatory disease of the airways, is a common condition, currently affecting about 9% of adults. Obesity is another disease with high prevalence in adults, and asthma that develops in ...

Rationale OPEP devices are often used therapeutically in order to aid airway clearance where excess mucus is a challenge, such as in bronchiectasis, CF and COPD. Ease of use, ability to clean and ...

Background There is minimal literature present on the role of physiotherapy in the management of Large Airway Collapse and airway clearance. Most articles state management should involve chest ...

Background Early detection of lung cancer saves lives, as demonstrated by the two largest published low-dose CT screening trials. Optimal implementation depends on our ability to identify those most ...

1 Centre for Workplace Health, Health and Safety Laboratory, Buxton, UK 2 Centre for Workplace Health, University of Sheffield, UK 3 Respiratory Function Unit, Royal Hallamshire Hospital, Sheffield, ...

Background It is current practice to use a single diagnostic sleep study in the diagnostic workup of obstructive sleep apnoea (OSA). However, a relevant night-to-night variability (NtNV) of ...

Crystalline silica, a primary mineral component of the Earth’s crust, is one of the most common occupational health hazards.

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Background Ultrafine particles (UFP; <0.1 µm in diameter) are not regulated or commonly monitored but may be harmful to human health, particularly for children. In this study, we aimed to examine the ...

Introduction Indwelling pleural catheter (IPC) has proved to be effective in reducing the need for further pleural procedures and hospital admissions in patients with malignant pleural effusion but ...

Concerns about the safety of long-acting β2-agonist (LABA) therapy, has led to the appearance of multiple publications and recommendations. This review critically examines the available clinical ...