The 49ers are 2-3 after losing to the Cardinals at home, and now they have to turn around and play the Seahawks in Seattle on ...

Tom Brady has improved as an announcer and showed how in the Arizona Cardinals' upset win over the San Francisco 49ers. Not ...

Watch San Francisco 49ers quarterback Brock Purdy's best plays vs. the Arizona Cardinals in the Week 5 matchup.

Jordan Mason continues to lead the 49ers ground game early in the season. The former undrafted free agent entered Sunday's contest as the NFL's second leading rusher with 447 yards and racked up 14 ...

Arizona shuts down San Francisco in second half to stage late rally after trailing by as much as 13 points on the road.

The Arizona Cardinals fumbled their way into the second half but rallied back for a 24-23 win over the San Francisco 49ers on Sunday.

Kyler Murray had a long touchdown run in the first quarter and rallied Arizona with two fourth-quarter scoring drives in the ...

Tom Brady awards Arizona Cardinals QB Kyler Murray with the LFG Player of the Game after his dominant performance against the ...

Even José Ramírez needed a quick reminder who Lane Thomas was. It was the eve of Trade Deadline Day and the first-place Guardians made their first splash by trading for Thomas. Ramírez met with local ...

The Arizona Cardinals fought the whole way through and it ended up being just enough at the very end to come away with a win.

San Francisco 49ers linebacker Dre Greenlaw shoved a Cardinals player in a sideline skirmish during Sunday's game, likely ...

Kyler Murray had a long touchdown run in the first quarter and rallied Arizona with two fourth-quarter scoring drives in the ...