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Researchers employed a gas chromatography-mass spectrometry (GC–MS)-based metabolomic approach combined with sophisticated statistical methods to identify metabolic biomarkers in coronary heart disease (CHD), hypertension-comorbid CHD, depression-comorbid CHD, and type 2 diabetes mellitus (T2DM)-comorbid CHD to provide an objective diagnostic method and help identify metabolomic signatures ...
About LCGC International - Chromatography Online
Jan 1, 2019 · Founded in 1983, LCGC International is the leading provider of digital and print content to the separation science market, enhancing the productivity, efficiency, and the overall value of separation techniques globally. With our commitment to editorial excellence, we have pioneered innovation across a broad portfolio of digital and print platforms.
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Practical advice, tutorials, and peer-reviewed research on liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) and related techniques.
Chromatography Fundamentals, Part VIII: The Meaning and …
Nov 1, 2019 · The effectiveness of a separation can be quantified by measuring the resolution. This article explains the factors influencing resolution and the equation for predicting the required number of theoretical plates to obtain a given esolution.
From Detector to Decision, Part III ... - Chromatography Online
Jan 1, 2024 · Gas chromatography is a premier technique for quantitative analysis. As gas chromatographs have become simpler to use and data systems more powerful, much of the data processing involved in delivering quantitative results now happens in the background and is seemingly invisible to the user. In this installment, we will review the calibration techniques used with gas chromatography.
Quantitative Metrics to Properly Describe Solute Elution in Size ...
Feb 16, 2024 · Where V r and t r are the conventional retention volume and time, respectively. In SEC–formally–V r and t r can be substituted by V e and t e.The value of the retention factor is -1 < k ≤ 0. Please note that the official symbols of a column’s hold-up time and volume are t M and V M, but in many research papers and handbooks, the hold-up time and volume are denoted as t …
Introduction to Preparative HPLC - Chromatography Online
Oct 1, 2012 · An overview of the principles and equipment required for scaling analytical separations to the preparative scale and considerations for the scale of analyte required.
Peak Purity in Liquid Chromatography, Part I: Basic Concepts ...
Feb 1, 2018 · where the bold face, lowercase letters denote vectors, or a list of the coordinates for the vector (three values in the present illustration; n values for the general n-dimensional case).The numerator represents the dot product of the two vectors, and the || || notation represents the vector norm, or in more conventional terms, the length of the given vector.
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Practical advice, tutorials, and peer-reviewed research on liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) and related techniques.
Solid-Phase Microextraction - Chromatography Online
Oct 1, 2012 · where K i,SPME is an aggregate solute distribution constant between the SPME absorptive layer and the sample, V SPME is the volume of the SPME layer, and C i is the solute concentration in the sample before performing SPME sampling.. Equation 1 assumes that the sample volume is much greater than the volume of the SPME layer. SPME coatings typically have thicknesses of about 10–100 µm ...