SOLVED: Draw a reasonable arrow-pushing mechanism for the following step in the reaction of glyceraldehyde 3-phosphate dehydrogenase. Use general bases and acids as needed. OPO3^2- + OPO3^2- + HO-NH2 → HO-NH2 + HO-NH2 How does the enzyme get away with using a horrible nucleophile like Pi during its turnover? Why is the product of this reaction so important for subsequent steps in the payoff phase?
SOLVED: Draw a reasonable arrow-pushing mechanism for the follow…
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