Metabolism (Ketogenesis and Ketolysis)
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Metabolism (Ketogenesis and Ketolysis)
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🔴SGLT2 Inhibitors: Cardio-Metabolic & Multiorgan Benefits Cardiovascular: Heart Failure: Cuts risk (HFrEF/HFpEF) with preload/afterload modulation, hemodynamic effects, and anti-inflammatory action. BP Reduction: Natriuresis-driven volume depletion enhances hypertension control. Metabolic Shift: Promotes ketogenesis & energy deficit, boosting myocardial efficiency. Renal Protection: Preserves eGFR, reduces albuminuria via tubuloglomerular feedback and antifibrotic effects. Metabolic/Liver: Impr
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🔴SGLT2 Inhibitors: Cardio-Metabolic & Multiorgan Benefits Cardiovascular: Heart Failure: Cuts risk (HFrEF/HFpEF) with preload/afterload modulation, hemodynamic effects, and anti-inflammatory action. BP Reduction: Natriuresis-driven volume depletion enhances hypertension control. Metabolic Shift: Promotes ketogenesis & energy deficit, boosting myocardial efficiency. Renal Protection: Preserves eGFR, reduces albuminuria via tubuloglomerular feedback and antifibrotic effects. Metabolic/Liver: Impr
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