The berberine containing herbs are highly antimicrobial and can generally kill any infection they can touch- but they have to touch it! So you can use the tea in a neti pot for sinus infections, a wash for skin infection, etc. as a bitter herb yellow root also encourages the digestive processes to get moving. Yellow root twigs were traditionally chewed in smoking cessation and served the dual function of giving people something to do with their hands and mouth while detoxing the body. | Walden F